Many times in the past I applied for less desirable positions, only to be told that I'm overqualified for them. Sometimes, the interviewers will bluntly ask me why I would want a job such as the one that I'm applying for, especially when I have a strong resume.
I recently communicated this problem to another neighbor. He suggested that I directly respond to these interviewers, "I want to take this jobs because when I become your boss, I want to know what I'm doing." That is a response you should give to any interviewer that tries to test the real reason you're applying for a position.